Clarence Seedorf And Patrick Kluivert appointment was announced by Cameroon’s Minister of Sport and Physical Education, Pierre Ismael Bidoung Mkpatt, at a news conference on Saturday and comes after talks with former England manager Sven-Goran Eriksson failed to reach an agreement.
Seedorf takes over from Hugo Broos, who led the side to a surprise victory at the 2017 African Nations Cup finals but was sackedin November after failing to win a place at the World Cup in Russia.
Alexandre Belinga had been acting as caretaker coach since.
Cameroon will defend their Nations Cup title on home soil in June next year, a first major finals test for the new management team.
Seedorf, 42, will take on his first national team job having had limited experience in coaching following brief spells with AC Milan, Chinese side Shenzhen and Deportivo La Coruna.
He was also capped 87 times by Netherlands between 1994 and 2008.
Patrick Kluivert was assistant coach to Netherlands boss Louis van Gaal between 2012 and 2014, and was later briefly in charge of Dutch Caribbean nation Curacao.